Artigo Acesso aberto Revisado por pares

Glomerular immune deposits are associated with increased proteinuria in patients with ANCA-associated crescentic nephritis

2003; Oxford University Press; Volume: 18; Issue: 3 Linguagem: Inglês

10.1093/ndt/18.3.524

ISSN

1460-2385

Autores

Irmgard Neumann,

Tópico(s)

Renal Diseases and Glomerulopathies

Resumo

Background. In small vessel vasculitis and its renal‐limited form, idiopathic crescentic glomerulonephritis, renal damage is characterized by pauci‐immune necrotizing crescentic glomerulonephritis (CGN) without histological evidence of immunoglobulin (Ig) deposition. In some patients, however, significant amounts of immune deposits may be detected. Therefore, we evaluated the clinical significance of these immune deposits in anti‐neutrophil cytoplasmic autoantibody (ANCA)‐associated pauci‐immune CGN.

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