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Gaining translational momentum: More zebrafish models for neuroscience research

2014; Elsevier BV; Volume: 55; Linguagem: Inglês

10.1016/j.pnpbp.2014.01.022

1878-4216

Allan V. Kalueff, David J. Echevarria, Adam Stewart,

Single-cell and spatial transcriptomics

Zebrafish (Danio rerio) are rapidly becoming a popular model organism in translational neuroscience and biological psychiatry research. Here we discuss conceptual, practical and other related aspects of using zebrafish in this field ("from tank to bedside"), and critically evaluate both advantages and limitations of zebrafish models of human brain disorders. We emphasize the need to more actively develop zebrafish models for neuroscience research focusing on complex traits.