The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels
2013; Elsevier BV; Volume: 121; Issue: 26 Linguagem: Inglês
10.1182/blood-2012-10-457507
ISSN1528-0020
AutoresNatalia Rydz, Laura L. Swystun, Colleen Notley, Andrew D. Paterson, J. Jacob Riches, Kate Sponagle, Boonchai Boonyawat, Robert R. Montgomery, Paula D. James, David Lillicrap,
Tópico(s)Renal Diseases and Glomerulopathies
ResumoKey Points CLEC4M plays a role in the clearance of VWF. CLEC4M polymorphisms contribute to the genetic variability of VWF plasma levels.
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