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BIBTEX RIS

Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon

2010; Instituto Oswaldo Cruz, Ministério da Saúde; Volume: 105; Issue: 2 Linguagem: Inglês

10.1590/s0074-02762010000200021

ISSN

1678-8060

Autores

Lena Líllian Canto de Sá, Érica L Fonseca, Maíra Pellegrini, Fernanda Freitas, Edvaldo Carlos Brito Loureiro, Ana Carolina Paulo Vicente,

Tópico(s)

Fecal contamination and water quality

Resumo

This study identified and characterised class 1 and 2 integrons in clinical and environmental Vibrio cholerae O1 and non-O1/non-O139 strains isolated from the Brazilian Amazon. The aadA2 and aadA7 gene cassettes were found in class 1 integrons in two genotypes of environmental V. cholerae non-O1/non-O139. Empty integrons were found in strains from the Brazilian cholera epidemic. A class 2 integron was detected in one strain from the V. cholerae Amazonia lineage harbouring sat1 and aadA1 genes. All isolates were resistant to aminoglycosides, indicating aadA functionality. These findings suggest that environmental bacteria act as cassette reservoirs that favour the emergence of resistant pathogens.

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