Synthesis of Benzopyran Linked Pyrrolo[2,1-c][1,4]benzodiazepines as DNA-Binding and Potential Anticancer Agents
2013; Bentham Science Publishers; Volume: 9; Issue: 2 Linguagem: Inglês
10.2174/1573406411309020003
ISSN1875-6638
AutoresÄhmed Kamal, Rajender, M. Kashi Reddy, Vangala Santhosh Reddy, G. Bharath Kumar,
Tópico(s)Cancer therapeutics and mechanisms
ResumoA series of twelve benzopyran linked pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) have been synthesized. They exhibit significant DNA-binding activity and excellent cytotoxic activity against various human cancer cell lines.
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