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Dynamic imaging of the lungs using x-ray phase contrast

2005; IOP Publishing; Volume: 50; Issue: 21 Linguagem: Inglês

10.1088/0031-9155/50/21/006

1361-6560

Robert A. Lewis, Naoto Yagi, Marcus J. Kitchen, Michael J. Morgan, David M. Paganin, Karen K. W. Siu, Konstantin M. Pavlov, Ivan Williams, Kentaro Uesugi, Megan J. Wallace, C.J. Hall, Jane C. Whitley, Stuart B. Hooper,

Nuclear Physics and Applications

High quality real-time imaging of lungs in vivo presents considerable challenges. We demonstrate here that phase contrast x-ray imaging is capable of dynamically imaging the lungs. It retains many of the advantages of simple x-ray imaging, whilst also being able to map weakly absorbing soft tissues based on refractive index differences. Preliminary results reported herein show that this novel imaging technique can identify and locate airway liquid and allows lung aeration in newborn rabbit pups to be dynamically visualized.