Portal de Periódicos da CAPES

Defining a Standard Set of Patient-centered Outcomes for Men with Localized Prostate Cancer

2014; Elsevier BV; Volume: 67; Issue: 3 Linguagem: Inglês

10.1016/j.eururo.2014.08.075

1873-7560

Neil E. Martin, Laura Massey, Caleb Stowell, Chris Bangma, Alberto Briganti, Anna Bill‐Axelson, Michael L. Blute, James W.F. Catto, Ronald C. Chen, Anthony V. D’Amico, Günter Feick, John M. Fitzpatrick, Steven J. Frank, Michael Froehner, Mark Frydenberg, Adam Glaser, Markus Graefen, Daniel A. Hamstra, Adam S. Kibel, Nancy P. Mendenhall, Kim Moretti, Jacob Ramon, Ian Roos, Howard M. Sandler, Francis Sullivan, David Swanson, Ashutosh Tewari, Andrew J. Vickers, Thomas Wiegel, Hartwig Huland,

Prostate Cancer Treatment and Research

Value-based health care has been proposed as a unifying force to drive improved outcomes and cost containment.To develop a standard set of multidimensional patient-centered health outcomes for tracking, comparing, and improving localized prostate cancer (PCa) treatment value.We convened an international working group of patients, registry experts, urologists, and radiation oncologists to review existing data and practices.The group defined a recommended standard set representing who should be tracked, what should be measured and at what time points, and what data are necessary to make meaningful comparisons. Using a modified Delphi method over a series of teleconferences, the group reached consensus for the Standard Set.We recommend that the Standard Set apply to men with newly diagnosed localized PCa treated with active surveillance, surgery, radiation, or other methods. The Standard Set includes acute toxicities occurring within 6 mo of treatment as well as patient-reported outcomes tracked regularly out to 10 yr. Patient-reported domains of urinary incontinence and irritation, bowel symptoms, sexual symptoms, and hormonal symptoms are included, and the recommended measurement tool is the Expanded Prostate Cancer Index Composite Short Form. Disease control outcomes include overall, cause-specific, metastasis-free, and biochemical relapse-free survival. Baseline clinical, pathologic, and comorbidity information is included to improve the interpretability of comparisons.We have defined a simple, easily implemented set of outcomes that we believe should be measured in all men with localized PCa as a crucial first step in improving the value of care.Measuring, reporting, and comparing identical outcomes across treatments and treatment centers will provide patients and providers with information to make informed treatment decisions. We defined a set of outcomes that we recommend being tracked for every man being treated for localized prostate cancer.