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Hepatitis E Virus Immunoglobulin G Antibodies in Different Populations in Campinas, Brazil

2000; American Society for Microbiology; Volume: 7; Issue: 5 Linguagem: Inglês

10.1128/cdli.7.5.813-816.2000

1098-6588

Neiva Sellan Lopes Gonçales, João Renato Rebello Pinho, Regina Célia Moreira, Cláudia Patara Saraceni, Ângela Maria Miranda Spina, R.B. Stucchi, Aírton D. Ribeiro Filho, Luís Alberto Magna, Fernando Lopes Gonçales Júnior,

Hepatitis B Virus Studies

ABSTRACT The seroprevalence of anti-hepatitis E virus (HEV) antibodies was investigated by enzyme immunoassay in 205 volunteer blood donors, 214 women who attended a center for anonymous testing for human immunodeficiency virus (HIV) infection, and 170 hospital employees in Campinas, a city in southeastern Brazil. The prevalence of anti-HEV antibodies ranged from 2.6% (3 of 117) in health care professionals to 17.7% (38 of 214) in women who considered themselves at risk for HIV. The prevalence of anti-HEV antibodies in health care professionals was not significantly different from that in healthy blood donors (3.0%, 5 of 165) and blood donors with raised alanine aminotransferase levels (7.5%, 3 of 40). The prevalence of anti-HEV antibodies (13.2%, 7 of 53) in cleaning service workers at a University hospital was similar to that among women at risk for HIV infection. These results suggest that HEV is circulating in southeastern Brazil and that low socioeconomic status is an important risk factor for HEV infection in this region.