Fentanyl Sparing Effects of Combined Ketorolac and Acetaminophen for Outpatient Inguinal Hernia Repair in Children
2010; Lippincott Williams & Wilkins; Volume: 183; Issue: 4 Linguagem: Inglês
10.1016/j.juro.2009.12.043
ISSN1527-3792
AutoresJeong‐Yeon Hong, Sang Won Han, Won Oak Kim, Hae Keum Kil,
Tópico(s)Anesthesia and Sedative Agents
ResumoNo AccessJournal of UrologyPediatric Urology1 Apr 2010Fentanyl Sparing Effects of Combined Ketorolac and Acetaminophen for Outpatient Inguinal Hernia Repair in Children Jeong-Yeon Hong, Sang Won Han, Won Oak Kim, and Hae Keum Kil Jeong-Yeon HongJeong-Yeon Hong , Sang Won HanSang Won Han , Won Oak KimWon Oak Kim , and Hae Keum KilHae Keum Kil View All Author Informationhttps://doi.org/10.1016/j.juro.2009.12.043AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: In this prospective, randomized, double-blinded study we sought to evaluate the efficacy and safety of combined use of intravenous ketorolac and acetaminophen in small children undergoing outpatient inguinal hernia repair. Materials and Methods: We studied 55 children 1 to 5 years old who were undergoing elective repair of unilateral inguinal hernia. After induction of general anesthesia children in the experimental group (28 patients) received 1 mg/kg ketorolac and 20 mg/kg acetaminophen intravenously. In the control group (27 patients) the same volume of saline was administered. All patients received 1 μg/kg fentanyl intravenously before incision. We also evaluated the number of patients requiring postoperative rescue fentanyl, total fentanyl consumption, pain scores and side effects. Results: Significantly fewer patients receiving ketorolac-acetaminophen received postoperative rescue fentanyl compared to controls (28.6% vs 81.5%). A significantly lower total dose of fentanyl was administered to patients receiving ketorolac-acetaminophen compared to controls (0.54 vs 1.37 μg/kg). Pain scores were significantly higher in the control group immediately postoperatively but eventually decreased. The incidences of sedation use (55.6% vs 25.0%) and vomiting (33.3% vs 10.7%) were significantly higher in controls. 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Volume 183Issue 4April 2010Page: 1551-1555 Advertisement Copyright & Permissions© 2010 by American Urological Association Education and Research, Inc.KeywordspainanalgesiapediatricsacetaminophenketorolacpostoperativeMetricsAuthor Information Jeong-Yeon Hong More articles by this author Sang Won Han More articles by this author Won Oak Kim More articles by this author Hae Keum Kil More articles by this author Expand All Advertisement PDF downloadLoading ...
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