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V/Q Scanning Using SPECT and SPECT/CT

2013; Society of Nuclear Medicine and Molecular Imaging; Volume: 54; Issue: 9 Linguagem: Inglês

10.2967/jnumed.113.124602

1535-5667

Paul Roach, Geoffrey Schembri, Dale L. Bailey,

Radiation Dose and Imaging

Planar ventilation-perfusion (V/Q) scanning is often used to investigate pulmonary embolism; however, it has well-recognized limitations. SPECT overcomes many of these through its ability to generate 3-dimensional imaging data. V/Q SPECT has higher sensitivity, specificity, and accuracy than planar imaging and a lower indeterminate rate. SPECT allows for new ways to display and analyze data, such as parametric V/Q ratio images. Compared with CT pulmonary angiography, SPECT has higher sensitivity, a lower radiation dose, fewer technically suboptimal studies, and no contrast-related complications. Any nuclear medicine department equipped with a modern hybrid scanner can now perform combined V/Q SPECT with CT (using low-dose protocols) to further enhance diagnostic accuracy. V/Q SPECT (with or without CT) has application in other pulmonary conditions and in research.