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Studying the co-evolution of protein families with the Mirrortree web server

2010; Oxford University Press; Volume: 26; Issue: 10 Linguagem: Inglês

10.1093/bioinformatics/btq137

1367-4811

David Ochoa, Florencio Pazos,

Bioinformatics and Genomic Networks

Abstract Summary: The Mirrortree server allows to graphically and interactively study the co-evolution of two protein families, and investigate their possible interactions and functional relationships in a taxonomic context. The server includes the possibility of starting from single sequences and hence it can be used by non-expert users. Availability and Implementation: The web server is freely available at http://csbg.cnb.csic.es/mtserver. It was tested in the main web browsers. Adobe Flash Player is required at the client side to perform the interactive assessment of co-evolution. Contact: pazos@cnb.csic.es Supplementary information: Supplementary data are available at Bioinformatics online.