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OXA-type carbapenemases

2006; Oxford University Press; Volume: 57; Issue: 3 Linguagem: Inglês

10.1093/jac/dki482

1460-2091

Jan Walther‐Rasmussen, Niels Høiby,

Bacterial biofilms and quorum sensing

In recent years, the number of class D β-lactamases with carbapenem-hydrolysing properties has increased substantially. Based on amino acid sequence identities, these class D or OXA-type carbapenemases are divided into eight distantly related groups, and they are only remotely related to other class D β-lactamases. A putative ancestor to one of the plasmid-encoded OXA-type carbapenemases has been found.