Ruthenium‐Catalyzed Regioselective Direct Alkylation of Arenes with Unactivated Alkyl Halides through CH Bond Cleavage
2009; Wiley; Volume: 48; Issue: 33 Linguagem: Inglês
10.1002/anie.200902458
ISSN1521-3773
AutoresLutz Ackermann, Petr Novák, R. Vicente, Nora Hofmann,
Tópico(s)Synthesis and Catalytic Reactions
ResumoCut to the chase: A ruthenium complex derived from 1-adamantyl carboxylate (1-AdCO2−) enabled highly regioselective intermolecular direct alkylation of arenes with unactivated primary and secondary alkyl halides bearing β-hydrogen atoms (see scheme; NMP=N-methylpyrrolidinone). Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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