The discontinuous nature of propagation in normal canine cardiac muscle. Evidence for recurrent discontinuities of intracellular resistance that affect the membrane currents.
1981; Lippincott Williams & Wilkins; Volume: 48; Issue: 1 Linguagem: Inglês
10.1161/01.res.48.1.39
ISSN1524-4571
AutoresMadison S. Spach, Wallace T. Miller, David B. Geselowitz, Roger C. Barr, J. Mailen Kootsey, Edward A. Johnson,
Tópico(s)Electrochemical Analysis and Applications
ResumoHomeCirculation ResearchVol. 48, No. 1The discontinuous nature of propagation in normal canine cardiac muscle. Evidence for recurrent discontinuities of intracellular resistance that affect the membrane currents. Free AccessAbstractPDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessAbstractPDF/EPUBThe discontinuous nature of propagation in normal canine cardiac muscle. Evidence for recurrent discontinuities of intracellular resistance that affect the membrane currents. M S Spach, W T Miller3rd, D B Geselowitz, R C Barr, J M Kootsey and E A Johnson M S SpachM S Spach Search for more papers by this author , W T Miller3rdW T Miller3rd Search for more papers by this author , D B GeselowitzD B Geselowitz Search for more papers by this author , R C BarrR C Barr Search for more papers by this author , J M KootseyJ M Kootsey Search for more papers by this author and E A JohnsonE A Johnson Search for more papers by this author Originally published1 Jan 1981https://doi.org/10.1161/01.RES.48.1.39Circulation Research. 1981;48:39–54 Previous Back to top Next FiguresReferencesRelatedDetailsCited By Karanfil M, Gündüzöz M, Karakurt M, Aruğaslan E, Özbay M, Ünal S, Akbuğa K, Akdi A, Erdöl M, Ertem A, Yayla Ç and Özeke Ö (2021) Effect of chelation therapy on arrhythmogenic and basal ECG parameters of lead exposed workers, Archives of Environmental & Occupational Health, 10.1080/19338244.2021.1910116, 77:5, (382-388), Online publication date: 28-May-2022. Lin J, Abraham A, George S, Greer-Short A, Blair G, Moreno A, Alber B, Kay M and Poelzing S (2022) Ephaptic Coupling Is a Mechanism of Conduction Reserve During Reduced Gap Junction Coupling, Frontiers in Physiology, 10.3389/fphys.2022.848019, 13 Sabzwari S, Rosenberg M, Mann J, Cerbin L, Barrett C, Garg L, Aleong R, Sandhu A, West J, Tumolo A, Varosy P, Sauer W, Zipse M and Tzou W (2022) Limitations of Unipolar Signals in Guiding Successful Outflow Tract Premature Ventricular Contraction Ablation, JACC: Clinical Electrophysiology, 10.1016/j.jacep.2022.03.013, Online publication date: 1-May-2022. Bakir A, Al Abed A, Lovell N and Dokos S Multiphysics Computational Modelling of the Cardiac Ventricles, IEEE Reviews in Biomedical Engineering, 10.1109/RBME.2021.3093042, 15, (309-324) Ciaccio E, Anter E, Coromilas J, Wan E, Yarmohammadi H, Wit A, Peters N and Garan H (2022) Structure and function of the ventricular tachycardia isthmus, Heart Rhythm, 10.1016/j.hrthm.2021.08.001, 19:1, (137-153), Online publication date: 1-Jan-2022. Roth B (2021) Bidomain modeling of electrical and mechanical properties of cardiac tissue, Biophysics Reviews, 10.1063/5.0059358, 2:4, (041301), Online publication date: 1-Dec-2021. van Schie M, Heida A, Taverne Y, Bogers A and de Groot N (2021) Identification of local atrial conduction heterogeneities using high-density conduction velocity estimation, EP Europace, 10.1093/europace/euab088, 23:11, (1815-1825), Online publication date: 8-Nov-2021. Irakoze É and Jacquemet V (2021) Multiparameter optimization of nonuniform passive diffusion properties for creating coarse-grained equivalent models of cardiac propagation, Computers in Biology and Medicine, 10.1016/j.compbiomed.2021.104863, 138, (104863), Online publication date: 1-Nov-2021. Lange M, Hirahara A, Ranjan R, Stoddard G, Dosdall D and Fukumoto Y (2021) Atrial slow conduction develops and dynamically expands during premature stimulation in an animal model of persistent atrial fibrillation, PLOS ONE, 10.1371/journal.pone.0258285, 16:10, (e0258285) Sankarankutty A, Greiner J, Bragard J, Visker J, Shankar T, Kyriakopoulos C, Drakos S and Sachse F (2021) Etiology-Specific Remodeling in Ventricular Tissue of Heart Failure Patients and Its Implications for Computational Modeling of Electrical Conduction, Frontiers in Physiology, 10.3389/fphys.2021.730933, 12 Rosales R, Mountris K, Doblare M, Mazo M and Pueyo E (2021) In Silico Electrophysiological Evaluation of Scaffold Geometries for Cardiac Tissue Engineering 2021 Computing in Cardiology (CinC), 10.23919/CinC53138.2021.9662890, 978-1-6654-7916-5, (1-4) Heida A, van Schie M, van der Does W, Taverne Y, Bogers A and de Groot N (2021) Reduction of Conduction Velocity in Patients with Atrial Fibrillation, Journal of Clinical Medicine, 10.3390/jcm10122614, 10:12, (2614) Rodríguez-Sinovas A, Sánchez J, Valls-Lacalle L, Consegal M and Ferreira-González I (2021) Connexins in the Heart: Regulation, Function and Involvement in Cardiac Disease, International Journal of Molecular Sciences, 10.3390/ijms22094413, 22:9, (4413) Anter E (2021) Limitations and Pitfalls of Substrate Mapping for Ventricular Tachycardia, JACC: Clinical Electrophysiology, 10.1016/j.jacep.2021.02.007, 7:4, (542-560), Online publication date: 1-Apr-2021. Sekihara T, Miyazaki S, Nagao M, Kakehashi S, Mukai M, Aoyama D, Nodera M, Eguchi T, Hasegawa K, Uzui H and Tada H (2020) Ultrahigh resolution electroanatomical mapping of the transverse conduction of the right atrial posterior wall in cases with and without typical atrial flutter, Journal of Cardiovascular Electrophysiology, 10.1111/jce.14850, 32:2, (297-304), Online publication date: 1-Feb-2021. Kotadia I, Whitaker J, Roney C, Niederer S, O’Neill M, Bishop M and Wright M (2020) Anisotropic Cardiac Conduction, Arrhythmia & Electrophysiology Review, 10.15420/aer.2020.04, 9:4, (202-210) Kharkovskaya E, Osipov G and Mukhina I Ventricular fibrillation induced by 2-aminoethoxydiphenyl borate under conditions of hypoxia/reoxygenation, Minerva Cardioangiologica, 10.23736/S0026-4725.20.05376-1, 68:6 Starreveld R and Groot N (2020) Direction‐ and rate‐dependent fractionation during atrial fibrillation persistence: Unmasking cardiac anisotropy?, Journal of Cardiovascular Electrophysiology, 10.1111/jce.14597, 31:8, (2206-2209), Online publication date: 1-Aug-2020. Perez-Alday E, Haq K, German D, Hamilton C, Johnson K, Phan F, Rogovoy N, Yang K, Wirth A, Thomas J, Dalouk K, Fuss C, Ferencik M, Heitner S and Tereshchenko L (2020) Mechanisms of Arrhythmogenicity in Hypertrophic Cardiomyopathy: Insight From Non-invasive Electrocardiographic Imaging, Frontiers in Physiology, 10.3389/fphys.2020.00344, 11 George S, Lin Z and Efimov I (2020) Basic Principles of Cardiac Electrophysiology Management of Cardiac Arrhythmias, 10.1007/978-3-030-41967-7_1, (3-32), . Centurión O, Alderete J, Candia J, García L, Scavenius K, Torales J and Miño L (2019) The association of low voltage atrial electrograms and the myocardial substrate for atrial fibrillation, Journal of Cardiology & Current Research, 10.15406/jccr.2019.12.00460, 12:6, (158-163) Qian S and Tarte E (2019) Finite element modelling of discontinuous action potential propagation in larval zebrafish and human cardiac tissue, Physical Biology, 10.1088/1478-3975/ab4d62, 17:1, (016001) Hoagland D, Santos W, Poelzing S and Gourdie R (2019) The role of the gap junction perinexus in cardiac conduction: Potential as a novel anti-arrhythmic drug target, Progress in Biophysics and Molecular Biology, 10.1016/j.pbiomolbio.2018.08.003, 144, (41-50), Online publication date: 1-Jul-2019. Jæger K, Edwards A, McCulloch A, Tveito A and Qu Z (2019) Properties of cardiac conduction in a cell-based computational model, PLOS Computational Biology, 10.1371/journal.pcbi.1007042, 15:5, (e1007042) Lee K, Choi J, Kim Y, Oh S, Kim D, Lee D, Roh S, Ahn J, Shim J, Park S and Kim Y (2019) Comparison between linear and focal ablation of complex fractionated atrial electrograms in patients with non-paroxysmal atrial fibrillation: a prospective randomized trial, EP Europace, 10.1093/europace/euy313, 21:4, (598-606), Online publication date: 1-Apr-2019. Fu G, He B, Wang B, Liu J, Yu Y, Du X, Feng M, Gao F, Jin H, Fang R and Chu H (2018) Unipolar electrogram-guided radiofrequency catheter ablation in paroxysmal atrial fibrillation: electrogram patterns and outcomes, Journal of Interventional Cardiac Electrophysiology, 10.1007/s10840-018-0470-8, 54:3, (203-208), Online publication date: 1-Apr-2019. Carmeliet E (2019) Conduction in cardiac tissue. Historical reflections, Physiological Reports, 10.14814/phy2.13860, 7:1, (e13860), Online publication date: 1-Jan-2019. Nguyên U, Verzaal N, van Nieuwenhoven F, Vernooy K and Prinzen F (2018) Pathobiology of cardiac dyssynchrony and resynchronization therapy, EP Europace, 10.1093/europace/euy035, 20:12, (1898-1909), Online publication date: 1-Dec-2018. Nguyên U, Potse M, Vernooy K, Mafi-Rad M, Heijman J, Caputo M, Conte G, Regoli F, Krause R, Moccetti T, Auricchio A, Prinzen F and Maffessanti F (2018) A left bundle branch block activation sequence and ventricular pacing influence voltage amplitudes: an in vivo and in silico study , EP Europace, 10.1093/europace/euy233, 20:suppl_3, (iii77-iii86), Online publication date: 1-Nov-2018. Bueno-Orovio A (2018) Commentary: Atrial Rotor Dynamics Under Complex Fractional Order Diffusion, Frontiers in Physiology, 10.3389/fphys.2018.01386, 9 Willis R (2018) Sinus Rhythms Guide to Canine and Feline Electrocardiography, 10.1002/9781119254355.ch5, (57-66) Gokhale T, Asfour H, Verma S, Bursac N, Henriquez C and McCulloch A (2018) Microheterogeneity-induced conduction slowing and wavefront collisions govern macroscopic conduction behavior: A computational and experimental study, PLOS Computational Biology, 10.1371/journal.pcbi.1006276, 14:7, (e1006276) Ciaccio E, Coromilas J, Wit A, Peters N and Garan H (2018) Source-Sink Mismatch Causing Functional Conduction Block in Re-Entrant Ventricular Tachycardia, JACC: Clinical Electrophysiology, 10.1016/j.jacep.2017.08.019, 4:1, (1-16), Online publication date: 1-Jan-2018. Verma B, Oesterlein T, Loewe A, Luik A, Schmitt C and Dössel O (2018) Regional conduction velocity calculation from clinical multichannel electrograms in human atria, Computers in Biology and Medicine, 10.1016/j.compbiomed.2017.11.017, 92, (188-196), Online publication date: 1-Jan-2018. Gokhale T, Medvescek E and Henriquez C (2017) Modeling dynamics in diseased cardiac tissue: Impact of model choice, Chaos: An Interdisciplinary Journal of Nonlinear Science, 10.1063/1.4999605, 27:9, (093909), Online publication date: 1-Sep-2017. Bortone A, Lagrange P, Cauchemez B, Durand C, Dieuzaide P, Prévot S, Mechulan A, Pambrun T, Martin R, Parlier P, Masse A, Marijon E and Albenque J (2017) Elimination of the negative component of the unipolar electrogram as a local procedural endpoint during paroxysmal atrial fibrillation catheter ablation using contact-force sensing: the UNIFORCE study, Journal of Interventional Cardiac Electrophysiology, 10.1007/s10840-017-0264-4, 49:3, (299-306), Online publication date: 1-Sep-2017. Rossi S, Buccarello A, Ershler P, Lux R, Callegari S, Corradi D, Carnevali L, Sgoifo A, Miragoli M, Musso E and Macchi E (2017) Effect of anisotropy on ventricular vulnerability to unidirectional block and reentry by single premature stimulation during normal sinus rhythm in rat heart, American Journal of Physiology-Heart and Circulatory Physiology, 10.1152/ajpheart.00366.2016, 312:3, (H584-H607), Online publication date: 1-Mar-2017. Prinzen F, Vernooy K, Lumens J and Auricchio A (2017) Physiology of Cardiac Pacing and Resynchronization Clinical Cardiac Pacing, Defibrillation and Resynchronization Therapy, 10.1016/B978-0-323-37804-8.00007-9, (213-248), . Crowcombe J, Dhillon S, Hurst R, Egginton S, Müller F, Sík A, Tarte E and Burgess H (2016) 3D Finite Element Electrical Model of Larval Zebrafish ECG Signals, PLOS ONE, 10.1371/journal.pone.0165655, 11:11, (e0165655) Tse G, Yan B, Chan Y, Tian X and Huang Y (2016) Reactive Oxygen Species, Endoplasmic Reticulum Stress and Mitochondrial Dysfunction: The Link with Cardiac Arrhythmogenesis, Frontiers in Physiology, 10.3389/fphys.2016.00313, 7 Haissaguerre M, Shah A, Cochet H, Hocini M, Dubois R, Efimov I, Vigmond E, Bernus O and Trayanova N (2016) Intermittent drivers anchoring to structural heterogeneities as a major pathophysiological mechanism of human persistent atrial fibrillation, The Journal of Physiology, 10.1113/JP270617, 594:9, (2387-2398), Online publication date: 1-May-2016. Hurtado D, Castro S and Gizzi A (2016) Computational modeling of non-linear diffusion in cardiac electrophysiology: A novel porous-medium approach, Computer Methods in Applied Mechanics and Engineering, 10.1016/j.cma.2015.11.014, 300, (70-83), Online publication date: 1-Mar-2016. Entz M, George S, Zeitz M, Raisch T, Smyth J and Poelzing S (2016) Heart Rate and Extracellular Sodium and Potassium Modulation of Gap Junction Mediated Conduction in Guinea Pigs, Frontiers in Physiology, 10.3389/fphys.2016.00016, 7 Zhang Y (2015) His electrogram alternans (Zhang’s phenomenon) and a new model of dual pathway atrioventricular node conduction, Journal of Interventional Cardiac Electrophysiology, 10.1007/s10840-015-0079-0, 45:1, (19-28), Online publication date: 1-Jan-2016. Tse G and Yeo J (2015) Conduction abnormalities and ventricular arrhythmogenesis: The roles of sodium channels and gap junctions, IJC Heart & Vasculature, 10.1016/j.ijcha.2015.10.003, 9, (75-82), Online publication date: 1-Dec-2015. PAMBRUN T, ROIG J, BOUZEMAN A, MAUPAS E, CIOBOTARU V, BOULENC J, APPETITI A, PUJADAS-BERTHAULT P, RIOUX P and BORTONE A (2015) Modification of the Unipolar Atrial Electrogram as a Local Endpoint During Common Atrial Flutter Ablation, Journal of Cardiovascular Electrophysiology, 10.1111/jce.12754, 26:11, (1196-1203), Online publication date: 1-Nov-2015. Doshi A, Walton R, Krul S, de Groot J, Bernus O, Efimov I, Boukens B and Coronel R (2015) Feasibility of a semi-automated method for cardiac conduction velocity analysis of high-resolution activation maps, Computers in Biology and Medicine, 10.1016/j.compbiomed.2015.05.008, 65, (177-183), Online publication date: 1-Oct-2015. Bakir A and Dokos S (2015) A gap junction-based cardiac electromechanics model 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 10.1109/EMBC.2015.7318252, 978-1-4244-9271-8, (25-28) Zou C, Song J, Li H, Huang X, Liu Y, Zhao C, Shi X and Yang X (2015) Right Ventricular Outflow Tract Septal Pacing Is Superior to Right Ventricular Apical Pacing, Journal of the American Heart Association, 4:4, Online publication date: 22-Apr-2015. Balycheva M, Faggian G, Glukhov A and Gorelik J (2015) Microdomain–specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling, Biophysical Reviews, 10.1007/s12551-014-0159-x, 7:1, (43-62), Online publication date: 1-Mar-2015. Takahashi K, Watanabe I, Kofune M, Ashino S, Iso K, Sasaki N, Kogawa R, Sonoda K, Okumura Y, Ohkubo K, Nakai T, Kunimoto S and Hirayama A (2015) Characteristics of Virtual Unipolar Electrogram Voltage and Characteristics of Isthmus Block during Radiofrequency Ablation of Typical Atrial Flutter, Journal of Nihon University Medical Association, 10.4264/numa.74.166, 74:4, (166-173), . Hoogendijk M and Coronel R (2015) J-wave syndrome(s), Trends in Cardiovascular Medicine, 10.1016/j.tcm.2014.09.012, 25:1, (22-23), Online publication date: 1-Jan-2015. Hoeker G and Poelzing S (2015) Moving beyond the reductionist approach—Time to put the pieces back together in a broken (infarcted) heart, Heart Rhythm, 10.1016/j.hrthm.2014.10.024, 12:1, (179-180), Online publication date: 1-Jan-2015. Adamson P, Vanoli E and Gronda E (2015) Risk for Sudden Cardiac Death in Heart Failure: Underlying Mechanisms and Therapeutic Modalities Pathophysiology and Pharmacotherapy of Cardiovascular Disease, 10.1007/978-3-319-15961-4_7, (129-149), . Bressan M, Louie J, Mikawa T and Panfilov A (2014) Hemodynamic Forces Regulate Developmental Patterning of Atrial Conduction, PLoS ONE, 10.1371/journal.pone.0115207, 9:12, (e115207) Bueno-Orovio A, Kay D, Grau V, Rodriguez B and Burrage K (2014) Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization, Journal of The Royal Society Interface, 10.1098/rsif.2014.0352, 11:97, (20140352), Online publication date: 6-Aug-2014. Linnenbank A, de Bakker J and Coronel R (2014) How to measure propagation velocity in cardiac tissue: a simulation study, Frontiers in Physiology, 10.3389/fphys.2014.00267, 5 Chávez-González E, González-Rodríguez E, Llanes-Camacho M, Garí-Llanes M, García-Nóbrega Y and García-Sáez J (2014) Dispersión de la onda P incrementada en niños dependiendo de la presión arterial, del peso, talla, de la estructura y función cardiaca, Archivos de Cardiología de México, 10.1016/j.acmx.2013.09.004, 84:3, (162-170), Online publication date: 1-Jul-2014. Henriquez C A Brief History of Tissue Models For Cardiac Electrophysiology, IEEE Transactions on Biomedical Engineering, 10.1109/TBME.2014.2310515, 61:5, (1457-1465) Veeraraghavan R, Poelzing S and Gourdie R (2014) Old cogs, new tricks: A scaffolding role for connexin43 and a junctional role for sodium channels?, FEBS Letters, 10.1016/j.febslet.2014.01.026, 588:8, (1244-1248), Online publication date: 17-Apr-2014. Veeraraghavan R, Gourdie R and Poelzing S (2014) Mechanisms of cardiac conduction: a history of revisions, American Journal of Physiology-Heart and Circulatory Physiology, 10.1152/ajpheart.00760.2013, 306:5, (H619-H627), Online publication date: 1-Mar-2014. Zhang Y (2014) Transverse versus longitudinal electrical propagation within the atrioventricular node during dual pathway conduction: Basis of dual pathway electrophysiology and His electrogram alternans (Zhang's phenomenon), International Journal of Cardiology, 10.1016/j.ijcard.2013.12.032, 171:2, (259-264), Online publication date: 1-Feb-2014. Yamashita S, Yoshida A, Fukuzawa K, Fujiwara R, Suzuki A, Nakanishi T, Matsumoto A, Konishi H, Ichibori H and Hirata K (2014) Upper Limit of Vulnerability During Defibrillator Implantations Predicts the Occurrence of Appropriate Shock Therapy for Ventricular Fibrillation, Circulation Journal, 10.1253/circj.CJ-14-0136, 78:7, (1606-1611), . Gonna H, Gallagher M, Guo X, Yap Y, Hnatkova K and Camm A (2013) P-Wave Abnormality Predicts Recurrence of Atrial Fibrillation after Electrical Cardioversion: A Prospective Study, Annals of Noninvasive Electrocardiology, 10.1111/anec.12087, 19:1, (57-62), Online publication date: 1-Jan-2014. Coronel R, Wilders R, Verkerk A, Wiegerinck R, Benoist D and Bernus O (2013) Electrophysiological changes in heart failure and their implications for arrhythmogenesis, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 10.1016/j.bbadis.2013.04.002, 1832:12, (2432-2441), Online publication date: 1-Dec-2013. Mazeh N, Haines D, Kay M and Roth B (2013) A Simplified Approach for Simultaneous Measurements of Wavefront Velocity and Curvature in the Heart Using Activation Times, Cardiovascular Engineering and Technology, 10.1007/s13239-013-0158-2, 4:4, (520-534), Online publication date: 1-Dec-2013. Romero L, Trenor B, Ferrero J, Starmer C and Bondarenko V (2013) Non-Uniform Dispersion of the Source-Sink Relationship Alters Wavefront Curvature, PLoS ONE, 10.1371/journal.pone.0078328, 8:11, (e78328) Kelly A, Ghouri I, Kemi O, Bishop M, Bernus O, Fenton F, Myles R, Burton F and Smith G (2013) Subepicardial Action Potential Characteristics Are a Function of Depth and Activation Sequence in Isolated Rabbit Hearts, Circulation: Arrhythmia and Electrophysiology, 6:4, (809-817), Online publication date: 1-Aug-2013. Da Costa A, Gabriel L, Romeyer-Bouchard C, Géraldine B, Gate-Martinet A, Laurence B, Levallois M and Isaaz K (2013) Focus on right ventricular outflow tract septal pacing, Archives of Cardiovascular Diseases, 10.1016/j.acvd.2012.08.005, 106:6-7, (394-403), Online publication date: 1-Jun-2013. De Mello W, Rivera M, Rabell A and Gerena Y (2012) Aliskiren, at low doses, reduces the electrical remodeling in the heart of the TGR(mRen2)27 rat independently of blood pressure, Journal of the Renin-Angiotensin-Aldosterone System, 10.1177/1470320312463832, 14:1, (23-33), Online publication date: 1-Mar-2013. Smaill B, Zhao J and Trew M (2013) Three-Dimensional Impulse Propagation in Myocardium, Circulation Research, 112:5, (834-848), Online publication date: 1-Mar-2013. Jichao Zhao , Butters T, Henggui Zhang , LeGrice I, Sands G and Smaill B Image-Based Model of Atrial Anatomy and Electrical Activation: A Computational Platform for Investigating Atrial Arrhythmia, IEEE Transactions on Medical Imaging, 10.1109/TMI.2012.2227776, 32:1, (18-27) van Deursen C, van Middendorp L and Prinzen F (2013) Dyssynchronous Heart Failure: From Bench to Bedside Translational Approach to Heart Failure, 10.1007/978-1-4614-7345-9_8, (169-203), . Himel H, Bub G, Lakireddy P and El-Sherif N (2012) Optical imaging of arrhythmias in the cardiomyocyte monolayer, Heart Rhythm, 10.1016/j.hrthm.2012.08.035, 9:12, (2077-2082), Online publication date: 1-Dec-2012. Saffitz J and Kléber A (2012) Gap Junctions, Slow Conduction, and Ventricular Tachycardia After Myocardial Infarction, Journal of the American College of Cardiology, 10.1016/j.jacc.2012.05.020, 60:12, (1111-1113), Online publication date: 1-Sep-2012. Fontes M, van Veen T, de Bakker J and van Rijen H (2012) Functional consequences of abnormal Cx43 expression in the heart, Biochimica et Biophysica Acta (BBA) - Biomembranes, 10.1016/j.bbamem.2011.07.039, 1818:8, (2020-2029), Online publication date: 1-Aug-2012. Nikolaidou T, Aslanidi O, Zhang H and Efimov I (2012) Structure–Function Relationship in the Sinus and Atrioventricular Nodes, Pediatric Cardiology, 10.1007/s00246-012-0249-0, 33:6, (890-899), Online publication date: 1-Aug-2012. García-Cosío F, Pastor Fuentes A and Núñez Angulo A (2012) Enfoque clínico de la taquicardia y el aleteo auricular desde su mecanismo: electrofisiología basada en la anatomía, Revista Española de Cardiología, 10.1016/j.recesp.2011.11.020, 65:4, (363-375), Online publication date: 1-Apr-2012. García-Cosío F, Pastor Fuentes A and Núñez Angulo A (2012) Clinical Approach to Atrial Tachycardia and Atrial Flutter From an Understanding of the Mechanisms. Electrophysiology Based on Anatomy, Revista Española de Cardiología (English Edition), 10.1016/j.rec.2011.11.013, 65:4, (363-375), Online publication date: 1-Apr-2012. Sperelakis N (2012) Cable Properties and Propagation of Action Potentials Cell Physiology Source Book, 10.1016/B978-0-12-387738-3.00018-4, (325-343), . Wang Y, DeMazumder D and Hill J (2012) Ionic Fluxes and Genesis of the Cardiac Action Potential Muscle, 10.1016/B978-0-12-381510-1.00007-7, (67-85), . Katritsis D and Camm A (2012) Clinical Electrophysiological Mechanisms of Tachycardias Arising from the Atrioventricular Junction Cardiac Arrhythmias and Mapping Techniques, 10.1007/978-0-85729-877-5_5, (151-177), . Wit A and Rosen M (2012) Cellular Electrophysiological and Genetic Mechanisms of Cardiac Arrhythmias Cardiac Arrhythmias and Mapping Techniques, 10.1007/978-0-85729-877-5_1, (3-52), . Zaza A, Wilders R and Opthof T (2012) Cellular Electrophysiology Basic Electrocardiology, 10.1007/978-0-85729-871-3_3, (105-144), . Noszczyk-Nowak A, Szałas A, Pasławska U and Nicpoń J (2011) Comparison of P-wave dispersion in healthy dogs, dogs with chronic valvular disease and dogs with disturbances of supraventricular conduction, Acta Veterinaria Scandinavica, 10.1186/1751-0147-53-18, 53:1, Online publication date: 1-Dec-2011. Bishop M, Vigmond E and Plank G (2011) Cardiac Bidomain Bath-Loading Effects during Arrhythmias: Interaction with Anatomical Heterogeneity, Biophysical Journal, 10.1016/j.bpj.2011.10.052, 101:12, (2871-2881), Online publication date: 1-Dec-2011. Takami M, Yoshida A, Fukuzawa K, Takei A, Kanda G, Takami K, Kumagai H, Tanaka S, Itoh M, Imamura K, Fujiwara R, Suzuki A and Hirata K (2011) Utility of virtual unipolar electrogram morphologies to detect transverse conduction block and turnaround points of typical atrial flutter, Journal of Interventional Cardiac Electrophysiology, 10.1007/s10840-011-9571-3, 32:2, (111-119), Online publication date: 1-Nov-2011. Stein M, van Veen T, Hauer R, de Bakker J, van Rijen H and Tjwa M (2011) A 50% Reduction of Excitability but Not of Intercellular Coupling Affects Conduction Velocity Restitution and Activation Delay in the Mouse Heart, PLoS ONE, 10.1371/journal.pone.0020310, 6:6, (e20310) Benson A, Bernus O, Dierckx H, Gilbert S, Greenwood J, Holden A, Mohee K, Plein S, Radjenovic A, Ries M, Smith G, Sourbron S and Walton R (2010) Construction and validation of anisotropic and orthotropic ventricular geometries for quantitative predictive cardiac electrophysiology, Interface Focus, 10.1098/rsfs.2010.0005, 1:1, (101-116), Online publication date: 6-Feb-2011. Tsumoto K, Ashihara T, Haraguchi R, Nakazawa K and Kurachi Y (2011) Roles of Subcellular Na + Channel Distributions in the Mechanism of Cardiac Conduction, Biophysical Journal, 10.1016/j.bpj.2010.12.3716, 100:3, (554-563), Online publication date: 1-Feb-2011. AKIYAMA T (2011) , Japanese Journal of Electrocardiology, 10.5105/jse.31.167, 31:2, (167-188), . de Diego C, Chen F, Xie Y, Pai R, Slavin L, Parker J, Lamp S, Qu Z, Weiss J and Valderrábano M (2011) Anisotropic conduction block and reentry in neonatal rat ventricular myocyte monolayers, American Journal of Physiology-Heart and Circulatory Physiology, 10.1152/ajpheart.00758.2009, 300:1, (H271-H278), Online publication date: 1-Jan-2011. Borek B, Glass L and Oldeman B (2011) Continuity of Resetting a Pacemaker in an Excitable Medium, SIAM Journal on Applied Dynamical Systems, 10.1137/100819229, 10:4, (1502-1524), Online publication date: 1-Jan-2011. Prinzen F, Strik M, Regoli F and Auricchio A (2011) Basic Physiology and Hemodynamics of Cardiac Pacing Clinical Cardiac Pacing, Defibrillation and Resynchronization Therapy, 10.1016/B978-1-4377-1616-0.00009-6, (203-233), . Végh Á and Papp R (2011) Possible Mechanisms of the Acute Ischemia-Induced Ventricular Arrhythmias: The Involvement of Gap Junctions Heart Rate and Rhythm, 10.1007/978-3-642-17575-6_29, (525-542), . Kléber A (2010) Na+ channel transfection to rescue propagation, Heart Rhythm, 10.1016/j.hrthm.2010.05.007, 7:8, (1111-1112), Online publication date: 1-Aug-2010. Dosdall D, Fast V and Ideker R (2010) Mechanisms of Defibrillation, Annual Review of Biomedical Engineering, 10.1146/annurev-bioeng-070909-105305, 12:1, (233-258), Online publication date: 1-Jul-2010. Pouliopoulos J, Sivagangabalan G, Barry M, Thiagalingam A, Huang K, Lu J, Byth K and Kovoor P (2010) Revised non-contact mapping of ventricular scar in a post-infarct ovine model with validation using contact mapping and histology, EP Europace, 10.1093/europace/euq098, 12:6, (881-889), Online publication date: 1-Jun-2010., Online publication date: 1-Jun-2010. Shaw R and Rudy Y (2010) Cardiac Muscle Is not a Uniform Syncytium, Biophysical Journal, 10.1016/j.bpj.2010.03.030, 98:12, (3102-3103), Online publication date: 1-Jun-2010. Deveci O, Aytemir K, Okutucu S, Tulumen E, Aksoy H, Kaya E, Evranos B, Kabakci G, Tokgozoglu L, Oto A and Ozkutlu H (2010) Evaluation of the Relationship between Atrial Septal Aneurysm and Cardiac Arrhythmias via P-Wave Dispersion and Signal-Averaged P-Wave Duration, Annals of Noninvasive Electrocardiology, 10.1111/j.1542-474X.2010.00357.x, 15:2, (157-164), Online publication date: 1-Apr-2010. Santilli R, Perego M, Perini A, Carli A, Moretti P and Spadacini G (2010) Radiofrequency catheter ablation of cavo-tricuspid isthmus as treatment of atrial flutter in two dogs, Journal of Veterinary Cardiology, 10.1016/j.jvc.2009.10.002, 12:1, (59-66), Online publication date: 1-Apr-2010. Jansen J, van Veen T, de Bakker J and van Rijen H (2010) Cardiac connexins and impulse propagation, Journal of Molecular and Cellular Cardiology, 10.1016/j.yjmcc.2009.08.018, 48:1, (76-82), Online publication date: 1-Jan-2010. Schrickel J and Lüderitz B (2010) Kardiale Elektrophysiologie Herzrhythmusstörungen, 10.1007/978-3-540-76755-8_2, (25-56), . Zaza A, Wilders R and Opthof T (2010) Cellular Electrophysiology Comprehensive Electrocardiology, 10.1007/978-1-84882-046-3_3, (105-144), . Katritsis D and Camm A (2010) Clinical Electrophysiological Mechanisms of Tachycardias Arising from theAtrioventricular Junction Comprehensive Electrocardiology, 10.1007/978-1-84882-046-3_27, (1231-1257), . Wit A and Rosen M (2010) Cellular Electrophysiological and Genetic Mechanisms of Cardiac Arrhythmias Comprehensive Electrocardiology, 10.1007/978-1-84882-046-3_23, (1083-1132), . Stein M, van Veen T, Remme C, Boulaksil M, Noorman M, van Stuijvenberg L, van der Nagel R, Bezzina C, Hauer R, de Bakker J and van Rijen H (2009) Combined reduction of intercellular coupling and membrane excitability differentially affects transverse and longitudinal cardiac conduction, Cardiovascular Research, 10.1093/cvr/cvp124, 83:1, (52-60), Online publication date: 1-Jul-2009. Aslanidi O, Stewart P, Boyett M and Zhang H (2009) Optimal Velocity and Safety of Discontinuous Conduction through the Heterogeneous Purkinje-Ventricular Junction, Biophysical Journal, 10.1016/j.bpj.2009.03.061, 97:1, (20-39), Online publication date: 1-Jul-2009. Aslanidi O, Benson A, Boyett M and Zhang H (2009) Mechanisms of defibrillation by standing waves in the bidomain ventricular tissue with voltage applied in an external bath, Physica D: Nonlinear Phenomena, 10.1016/j.physd.2009.02.003, 238:11-12, (984-991), Online publication date: 1-Jun-2009. Wikswo J and Roth B Virtual Electrode Theory of Pacing Cardiac Bioelectric Therapy, 10.1007/978-0-387-79403-7_12, (283-330) Fedorov V, Glukhov A, Sudharshan S, Egorov Y, Rosenshtraukh L and Efimov I (2008
Referência(s)