Artigo Acesso aberto Revisado por pares

In Vitro Killing of Community-Associated Methicillin-Resistant Staphylococcus aureus with Drug Combinations

2004; American Society for Microbiology; Volume: 48; Issue: 10 Linguagem: Inglês

10.1128/aac.48.10.4016-4019.2004

ISSN

1098-6596

Autores

Samuel A. Shelburne, Daniel M. Musher, Kristina G. Hultén, Heather Ceasar, Michael Lu, Imran Bhaila, Richard J. Hamill,

Tópico(s)

Bacterial Identification and Susceptibility Testing

Resumo

This study employs time-kill techniques to examine the most common drug combinations used in the therapy of methicillin-resistant Staphylococcus aureus (MRSA) infections, vancomycin plus either gentamicin or rifampin. Community-associated MRSA were more likely to be synergistically inhibited by combinations of vancomycin and gentamicin versus vancomycin alone compared to inhibition associated with hospital-acquired strains.

Referência(s)