In Vitro Killing of Community-Associated Methicillin-Resistant Staphylococcus aureus with Drug Combinations
2004; American Society for Microbiology; Volume: 48; Issue: 10 Linguagem: Inglês
10.1128/aac.48.10.4016-4019.2004
ISSN1098-6596
AutoresSamuel A. Shelburne, Daniel M. Musher, Kristina G. Hultén, Heather Ceasar, Michael Lu, Imran Bhaila, Richard J. Hamill,
Tópico(s)Bacterial Identification and Susceptibility Testing
ResumoThis study employs time-kill techniques to examine the most common drug combinations used in the therapy of methicillin-resistant Staphylococcus aureus (MRSA) infections, vancomycin plus either gentamicin or rifampin. Community-associated MRSA were more likely to be synergistically inhibited by combinations of vancomycin and gentamicin versus vancomycin alone compared to inhibition associated with hospital-acquired strains.
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