Produção Nacional
Changes in the lung following injections of Silicone gel
1975; Elsevier BV; Volume: 28; Issue: 3 Linguagem: Inglês
10.1016/0007-1226(75)90124-1
ISSN1465-3087
AutoresMarcus Castro Ferreira, V Spina, K Iriya,
Tópico(s)Intramuscular injections and effects
ResumoSILICONES for reconstructive surgery may be in solid, liquid or gel form.The inertness of solid silicone in so far as it is unchanged by contact with the tissues is well established.On the other hand Silicone Fluid1 of 350 centistokes viscosity is phagocytosed by a variety of cells after injection and can find its way into various organs.(For a full review of solid and liquid silicones see Blocksma and Braley, 1973.)Although silicone gel makes up most of the bulk of many breast prostheses, it is not in contact with the tissues.Indeed silicone gel on its own has been little used in Britain and North America; although Spira and Hardy (1971) and Freeman (1974) have implanted Silastic gel obtained by opening a breast prosthesis they were unable to obtain the material in any other way.By contrast, Elicon' silicone gel injections have been widely used in the Orient, Europe and South America mainly for breast augmentation (Uchida, 1956(Uchida, , 1961;;Yoon, 1964; Mutou, 1965; Pigossi, 1972).The complications are also well known (Boo Chai, 1969; Mutou, 1970).Spira and Hardy implanted Silasticl gel from breast prostheses into rats and mice and claimed that there was "no spread or dissemination of the gel to either lymph nodes or major organs".It seemed to us strange that we could find no trace of a similar experimental study of the much more widely used Elicon gel and the following investigation was undertaken.
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