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Human Skeletal Remains from the Kofun Period in Japan Speculated to Have Had Osseous Dysplasia with Inflammation

2006; Elsevier BV; Volume: 48; Issue: 4 Linguagem: Inglês

10.1016/s1349-0079(06)80008-3

1880-3865

Hisashi Fujita, Hirohiko Hirano, Takao Suzuki,

Bone health and treatments

Signs of disease thought to indicate a fibro-osseous disorder were found in a mandible of human skeletal remains from the Kofun period in Japan. The skeletal remains were found in an excavation in Yamato City, Kanagawa Prefecture. Fibro-osseous disorder encompasses several diseases. The case in this report was a male in his 30s who had bilateral lesions in the mandibular molar regions with bony structures having well-defined margins. The left molar region showed considerable destructive resorption towards the mandibular base, and periosteomyelitis was thought to have accompanied it. The differential diagnosis of fibro-osseous disorder is difficult. However, the lesions were speculated to be osseous dysplasia based on radio-opacities on radiographs and CT scans and the lack of metastasis in the bones of the trunk, in addition to other findings. In other words, the lesions were comprehensively determined to have been benign and not malignant. No previous report has been made on the discovery of osseous dysplasia in excavated ancient human skeletal remains. Therefore, this case is considered to be very important.