Probing the Validity of the Probe-to-Bone Test in the Diagnosis of Osteomyelitis of the Foot in Diabetes
2006; American Diabetes Association; Volume: 29; Issue: 4 Linguagem: Inglês
10.2337/diacare.29.04.06.dc05-2450
ISSN1935-5548
AutoresAlison E. Shone, Jaclyn Burnside, Susan Chipchase, Frances L. Game, William Jeffcoate,
Tópico(s)Hematological disorders and diagnostics
ResumoThe ability to probe the base of a wound to periosteum or bone (the “probe-to-bone” test) is increasingly used to indicate the likelihood of underlying osteomyelitis. The original study (1) reported sensitivity, specificity, and positive (PPV) and negative (NPV) predictive values of 66, 85, 89, and 56%, respectively. However, this work has been criticized on the grounds of the high pretest probability of the disease (2), since the prevalence of osteomyelitis in the chosen sample (in-patients with clinically overt infection) was 66%. It follows that the usefulness of the test may be very different in less-selected populations. We have therefore determined the validity of the probe-to-bone test in a consecutive series of outpatients attending our own multi
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