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Pharmacological treatment of children with gastro-oesophageal reflux

2014; Elsevier BV; Volume: 2016; Issue: 11 Linguagem: Inglês

10.1002/14651858.cd008550.pub2

1465-1858

Mark Tighe, Nadeem Afzal, Amanda Bevan, Andrew Hayen, A. Munro, R. Mark Beattie,

Respiratory and Cough-Related Research

Gastro-oesophageal reflux (GOR) is a common disorder, characterised by regurgitation of gastric contents into the oesophagus. GOR is a very common presentation in infancy in both primary and secondary care settings. GOR can affect approximately 50% of infants younger than three months old (Nelson 1997). The natural history of GOR in infancy is generally that of a functional, self-limiting condition that improves with age; < 5% of children with vomiting or regurgitation continue to have symptoms after infancy (Martin 2002). Older children and children with co-existing medical conditions can have a more protracted course. The definition of gastro-oesophageal reflux disease (GORD) and its precise distinction from GOR are debated, but consensus guidelines from the North American Society of Gastroenterology, Hepatology and Nutrition (NASPGHAN-ESPGHAN guidelines 2009) define GORD as 'troublesome symptoms or complications of GOR.'