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Multifocal sporotrichosis with meningeal involvement in a patient with AIDS

2005; Oxford University Press; Volume: 43; Issue: 2 Linguagem: Inglês

10.1080/13693780500035904

1460-2709

Mário León Silva-Vergara, Frederico Ricardo Zago Maneira, Renata Mônica De Oliveira, Celso Tadeu Barbosa dos Santos, Renata Margarida Etchebehere, Sheila Jorge Adad,

Plant Pathogens and Fungal Diseases

This report describes a 29-year-old man with AIDS and disseminated lymphocutaneous sporotrichosis diagnosis presenting a poor therapeutic adhesion to itraconazole therapy that later evolved to neurological impairment and death. Necropsy showed granulomatous reaction and yeast-like forms similar to Sporothrix schenckii in meninges, lymph nodes, marrow bone, skin, testicles, epididymides and pancreas. Meningeal sporotrichosis cases associated to AIDS are reviewed in brief.