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Changes in Continence and Erectile Function Between 2 and 4 Years After Radical Prostatectomy

2008; Lippincott Williams & Wilkins; Volume: 181; Issue: 2 Linguagem: Inglês

10.1016/j.juro.2008.10.019

1527-3792

Leonard Glickman, Guilherme Godoy, Herbert Lepor,

Urinary Bladder and Prostate Research

No AccessJournal of UrologyAdult Urology1 Feb 2009Changes in Continence and Erectile Function Between 2 and 4 Years After Radical Prostatectomy Leonard Glickman, Guilherme Godoy, and Herbert Lepor Leonard GlickmanLeonard Glickman , Guilherme GodoyGuilherme Godoy , and Herbert LeporHerbert Lepor View All Author Informationhttps://doi.org/10.1016/j.juro.2008.10.019AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: There is a paucity of information on changes in continence and erectile function beyond 2 years after radical prostatectomy. We prospectively examined changes in continence and erectile function between 2 and 4 years after radical prostatectomy. Materials and Methods: Between October 2000 and August 2003, 731 consecutive men underwent open retropubic radical prostatectomy for clinically localized prostate cancer. Preoperative and postoperative continence, and erectile function were ascertained using the UCLA Prostate Cancer Index. The 48-month prospective self-assessment followup questionnaire captured changes in urinary control and erectile function between 24 and 48 months, including marked, moderate or slight improvement, no change or worsening. Results: Overall between 24 and 48 months after radical prostatectomy 23.4% and 42.3% of men showed any degree of improvement in continence and erectile function, and 12.2% and 19.8% showed marked and moderate improvement in continence and erectile function, respectively. The probability of experiencing any qualitative improvement in urinary continence was not significantly different in men who were continent or incontinent at 24 months. The likelihood of experiencing any qualitative improvement in erectile function was significantly greater in men who were potent at 24 months compared to those who were impotent. Conclusions: Our study provides compelling evidence that clinically significant improvements in urinary control and erectile function occur beyond 2 years after radical prostatectomy. These qualitative improvements are greatest for erectile function in men who were potent at 2 years. Therefore, men should not be counseled that maximal urinary continence or erectile function are achieved by 24 months after radical prostatectomy. References 1 : The impact of open radical retropubic prostatectomy on continence and lower urinary tract symptoms: a prospective assessment using validated self-administered outcome instruments. J Urol2004; 171: 1216. Link, Google Scholar 2 : Prospective assessment of patient reported urinary continence after radical prostatectomy. J Urol2000; 164: 744. Link, Google Scholar 3 : Urinary continence after radical prostatectomy: the Columbia experience. J Urol1998; 159: 1276. Link, Google Scholar 4 : Impact of anatomical radical prostatectomy on urinary continence. 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A Prospective Multi-Institutional Study Using Independently Collected, Validated QuestionnairesJournal of Urology, VOL. 207, NO. 5, (1048-1056), Online publication date: 1-May-2022.Prabhu V, Alukal J, Laze J, Makarov D and Lepor H (2018) Long-Term Satisfaction and Predictors of Use of Intracorporeal Injections for Post-Prostatectomy Erectile DysfunctionJournal of Urology, VOL. 189, NO. 1, (238-242), Online publication date: 1-Jan-2013.Abraham N, Makarov D, Laze J, Stefanovics E, Desai R and Lepor H (2018) Patient Centered Outcomes in Prostate Cancer Treatment: Predictors of Satisfaction Up to 2 Years After Open Radical Retropubic ProstatectomyJournal of Urology, VOL. 184, NO. 5, (1977-1981), Online publication date: 1-Nov-2010. Volume 181Issue 2February 2009Page: 731-735 Advertisement Copyright & Permissions© 2009 by American Urological AssociationKeywordsurinary incontinenceprostatectomyerectile dysfunctionprostatepostoperative complicationsMetricsAuthor Information Leonard Glickman More articles by this author Guilherme Godoy More articles by this author Herbert Lepor Financial interest and/or other relationship with Medreviews, Aeterna Zentaris, Watson Pharmaceuticals and US HIFU. More articles by this author Expand All Advertisement PDF downloadLoading ...