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A Review of Streptococcus pneumoniae Infection Treatment Failures Associated with Fluoroquinolone Resistance

2005; Oxford University Press; Volume: 41; Issue: 1 Linguagem: Inglês

10.1086/430829

1537-6591

Jonathan Fuller, Donald E. Low,

Antimicrobial Resistance in Staphylococcus

We reviewed all of the published reports of cases of fluoroquinolone treatment failures for respiratory tract infection due to fluoroquinolone-resistant Streptococcus pneumoniae. There were 20 ciprofloxacin and levofloxacin treatment failures reported. Physicians should be aware, when treating pneumococcal respiratory tract infections in older patients with a fluoroquinolone, that clinical failures might occur, especially for patients with comorbid illnesses and a history of recent fluoroquinolone use.