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Evaluation of questionnaire on cancer family history in identifying patients at increased genetic risk in general practice

1999; BMJ; Volume: 319; Issue: 7212 Linguagem: Inglês

10.1136/bmj.319.7212.757

0959-8138

V. Leggatt, James Mackay, John R.W. Yates,

Colorectal Cancer Screening and Detection

Patients at increased genetic risk of breast or colorectal cancer who may benefit from screening can be identified from their family histories 12 For those at risk of colorectal cancer, colonoscopic surveillance reduces the incidence of disease.3 For those at risk of breast cancer, the results of mammographic screening are encouraging but more data are needed to confirm benefit.4 Currently, patients with indicative family histories who consult their general practitioners are often referred to clinics for cancer genetics. Others with similar family histories who are less aware of the familial nature of these cancers or of the availability of screening do not seek advice. If improving knowledge about the genetics of familial cancers and other common diseases is to benefit all patients and not just those who are better informed, strategies need to be developed to identify those at risk. We investigated the feasibility of using a postal questionnaire to identify patients in a general practice at increased genetic risk of breast or …