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Detection and Identification of Ketamine and its Metabolites in Horse Urine

1987; Oxford University Press; Volume: 11; Issue: 2 Linguagem: Inglês

10.1093/jat/11.2.58

1945-2403

Richard A. Sams, Pat Pizzo,

Veterinary Equine Medical Research

The possibility exists that ketamine, or ketamine in combination with xylazine, is being used illicitly to affect the performance of racehorses. This study was undertaken to identify the metabolites of ketamine in the urine of adult horses and to evaluate methods for detecting and confirming ketamine administration. Detection of ketamine and two ketamine metabolites is described using thin-layer chromatography (TLC) and their identities are confirmed by comparing their mass spectra and gas chromatographic retention times with those of authentic standards.