Isolation and structure elucidation of novel hypotensive agents, niazinin A, niazinin B, niazimicin and niaziminin A + B from Moringa oleifera: the first naturally occurring thiocarbamates

1992; Issue: 23 Linguagem: Inglês

10.1039/p19920003237

ISSN

2050-8255

Autores

Shaheen Faizi, Bina S. Siddiqui, Rubeena Saleem, Salimuzzaman Siddiqui, Khalid Aftab, Anwarul Hassan Gilani,

Tópico(s)

Phytochemistry and Bioactivity Studies

Resumo

Novel hypotensive principles, niazinin A 1, niazinin B 2, niazimicin 4 and niaziminin A and B 6+7, have been obtained from the ethanolic extract of the fresh leaves of Moringa oleifera, employing a bioassay-guided isolation procedure. Their structures have been elucidated through spectroscopic (including 2D NMR techniques) and chemical methods. These compounds are mustard oil glycosides which are very rare in Nature and are also the first examples of naturally occurring thiocarbamates.

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