Produção Nacional
Impact of plasmatic lipids in glycemic control and its influence in the cardiometabolic risk in morbidly obese subjects
2009; Editora da Universidade de São Paulo; Volume: 53; Issue: 6 Linguagem: Inglês
10.1590/s0004-27302009000600009
ISSN1677-9487
AutoresAry Serpa Neto, Felipe Martin Bianco Rossi, Rodrigo Dal Moro Amarante, Nara Alves Buriti, Marçal Rossi,
Tópico(s)Metabolism, Diabetes, and Cancer
ResumoTo evaluate whether biochemical parameters are associated with a good glycemic control and to identify the occurrence of cardiometabolic risk variables.One hundred forty Brazilians were evaluated. The subjects were characterized with regard to glycemic control as good, fair and poor and were divided into tertiles by TG and HbA(1c). We use the ROC curve to determine which variables were predicted of poor glycemic control and the factor analyses to identify the domains that segregated among the risk variables.Fasting glucose and insulin levels, TG level, VLDL-C and HOMA-IR increased significantly across HbA(1c) tertiles. The best marker for identification of poor glycemic control was triglycerides. The presence of cardiometabolic abnormalities did not alter the glycemic control, but HOMA-IR was significantly higher in subjects with abnormalities.The use of TG levels offers a reasonable degree of clinical utility. In morbidly obese subjects insulin resistance is associated with individual cardiometabolic factors.
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