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Temporal pole signal abnormality on MR imaging in temporal lobe epilepsy with hippocampal sclerosis: a fluid-attenuated inversion-recovery study

2007; Thieme Medical Publishers (Germany); Volume: 65; Issue: 3a Linguagem: Inglês

10.1590/s0004-282x2007000400001

1678-4227

Henrique Carrete, Nitamar Abdala, Kátia Lin, Luís Otávio Sales Ferreira Caboclo, Ricardo Silva Centeno, Américo Ceiki Sakamoto, Jacob Szjenfeld, Roberto Gomes Nogueira, Elza Márcia Targas Yacubian,

Neurological disorders and treatments

OBJECTIVE: To determine the frequency and regional involvement of temporal pole signal abnormality (TPA) in patients with hippocampal sclerosis (HS) using fluid-attenuated inversion-recovery (FLAIR) MR imaging, and to correlate this feature with history. METHOD: Coronal FLAIR images of the temporal pole were assessed in 120 patients with HS and in 30 normal subjects, to evaluate gray-white matter demarcation. RESULTS: Ninety (75%) of 120 patients had associated TPA. The HS side made difference regarding the presence of TPA, with a left side prevalence (p=0.04, chi2 test). The anteromedial zone of temporal pole was affected in 27 (30%) out of 90 patients. In 63 (70%) patients the lateral zone were also affected. Patients with TPA were younger at seizure onset (p=0.018), but without association with duration of epilepsy. CONCLUSION: Our FLAIR study show temporal pole signal abnormality in 3/4 of patients with HS, mainly seen on the anteromedial region, with a larger prevalence when the left hippocampus was involved.