
Generation of Superoxide Anions and Hydrogen Peroxide from β-Lapachone in Bacteria
1978; American Society for Microbiology; Volume: 14; Issue: 4 Linguagem: Inglês
10.1128/aac.14.4.630
ISSN1098-6596
AutoresFernando S. Cruz, Roberto Docampo, Alberto Boveris,
Tópico(s)Synthesis and Biological Evaluation
Resumobeta-Lapachone markedly increased the generation of superoxide anions and hydrogen peroxide by subcellular membranes of Bacillus subtilis and Bacillus stearothermophilus. Peroxide generation by beta-lapachone was parallel to the inhibition of growth in both microorganisms.
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