Artigo Acesso aberto Produção Nacional Revisado por pares

Generation of Superoxide Anions and Hydrogen Peroxide from β-Lapachone in Bacteria

1978; American Society for Microbiology; Volume: 14; Issue: 4 Linguagem: Inglês

10.1128/aac.14.4.630

ISSN

1098-6596

Autores

Fernando S. Cruz, Roberto Docampo, Alberto Boveris,

Tópico(s)

Synthesis and Biological Evaluation

Resumo

beta-Lapachone markedly increased the generation of superoxide anions and hydrogen peroxide by subcellular membranes of Bacillus subtilis and Bacillus stearothermophilus. Peroxide generation by beta-lapachone was parallel to the inhibition of growth in both microorganisms.

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