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Clinical Criteria for the Diagnosis of Vascular Dementia

2000; American Medical Association; Volume: 57; Issue: 2 Linguagem: Inglês

10.1001/archneur.57.2.191

1538-3687

Helena C. Chui, Wendy J. Mack, J. Edward Jackson, Daniel Mungas, Bruce R. Reed, Jared Tinklenberg, Fen‐Lei Chang, Kate Skinner, Cora Tasaki, William J. Jagust,

Neurological Disorders and Treatments

Background: Several clinical criteria have been developed to standardize the diagnosis of vascular dementia (VaD).Significant differences in patient classification have been reported, depending on the criteria used.Few studies have examined interrater reliability.Objective: To assess the concordance in classification and interrater reliability for the following 4 clinical definitions of VaD: the Hachinski Ischemic Score (HIS), the Alzheimer Disease Diagnostic and Treatment Centers (ADDTC), National Institute of Neurological Disorders and Stroke-Association Internationale pour la Recherche et l'Enseignement en Neurosciences (NINDS-AIREN), and Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV).Methods: Structured diagnostic checklists were developed for 4 criteria for VaD, 2 criteria for Alzheimer disease (AD), and 4 criteria for dementia.Twenty-five case vignettes, representing a spectrum of cognitive impairment and subtypes of dementia, were prepared in a stan-