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Biyouyanagin A, an Anti-HIV Agent from Hypericum c hinense L. var. s alicifolium

2005; American Chemical Society; Volume: 7; Issue: 14 Linguagem: Inglês

10.1021/ol050960w

1523-7060

Naonobu Tanaka, Mamoru Okasaka, Youko Ishimaru, Yoshihisa Takaishi, Mitsunobu Sato, Masato Okamoto, Tetsuya Oshikawa, Sharif Ahmed, L. Mark Consentino, Kuo‐Hsiung Lee,

Synthesis of Organic Compounds

[structure: see text] A structurally unique hydrophobic compound, biyouyanagin A, was isolated from the MeOH extract of the leaves of Hypericum chinense L. var. salicifolium. The structure of biyouyanagin A was elucidated on the basis of spectroscopic evidence. Biyouyanagin A showed a significant activity against HIV and inhibited cytokine production.