Artigo Revisado por pares

Favorable Outcome of Pregnancy with an Elective Use of Epoprostenol and Sildenafil in Women with Severe Pulmonary Hypertension

2010; Karger Publishers; Volume: 115; Issue: 3 Linguagem: Inglês

10.1159/000287638

ISSN

1421-9751

Autores

Sorel Goland, Fausen Tsai, Munira Habib, Munir Janmohamed, T. Murphy Goodwin, Uri Elkayam,

Tópico(s)

Cardiovascular Issues in Pregnancy

Resumo

<i>Background:</i> Pulmonary hypertension carries significant maternal and fetal risk during pregnancy and the postpartum period. As maternal mortality is high, specific targeted therapy for pulmonary hypertension may be required during pregnancy. <i>Cases:</i> We describe 2 pregnant patients who presented with severe secondary pulmonary arterial hypertension during their last trimester. They were electively treated in the late antepartum and early postpartum periods with sildenafil and intravenous epoprostenol and successfully delivered healthy infants via cesarean section without postpartum complications. <i>Conclusion:</i> Although pulmonary hypertension is associated with a risk of maternal mortality and most women are advised against pregnancy, new therapies may improve the outcome of pregnancy in patients with pulmonary hypertension.

Referência(s)
Altmetric
PlumX