Artigo Acesso aberto Produção Nacional Revisado por pares

Complicated intra-abdominal infections in a worldwide context: an observational prospective study (CIAOW Study)

2013; BioMed Central; Volume: 8; Issue: 1 Linguagem: Inglês

10.1186/1749-7922-8-1

ISSN

1749-7922

Autores

Massimo Sartelli, Fausto Catena, Luca Ansaloni, Ernest E. Moore, Mark A. Malangoni, George C. Velmahos, Raúl Coimbra, Kaoru Koike, Ari Leppäniemi, Walter Biffl, Zsolt J. Balogh, Cino Bendinelli, Sanjay Gupta, Yoram Kluger, Ferdinando Agresta, Salomone Di Saverio, Gregorio Tugnoli, Elio Jovine, Carlos A. Ordóñez, Carlos Augusto Gomes, Gerson Alves Pereira Júnior, Kuo-Ching Yuan, Miklosh Bala, Miroslav P. Peev, Yunfeng Cui, Sanjay Marwah, Sanoop Koshy Zachariah, Boris Sakakushev, Victor Kong, Adamu Ahmed, Ashraf Abbas, Ricardo Alessandro Teixeira Gonsaga, Gianluca Guercioni, Nereo Vettoretto, Elia Poiasina, Offir Ben‐Ishay, Rafael Díaz-Nieto, Damien Massalou, M Škrovina, Ihor Gerych, Goran Augustin, Jakub Kenig, Vladimir Khokha, Cristian Tranà, Kenneth Yuh Yen Kok, Alain Chichom‐Mefire, Jae Gil Lee, Suk‐Kyung Hong, Helmut Alfredo Segovia Lohse, Wagih Ghnnam, Alfredo Verni, Varut Lohsiriwat, Boonying Siribumrungwong, Alberto Tavares, Gian Luca Baiocchi, Koray Daş, Julien Jarry, M Zida, Norio Sato, Kiyoshi Murata, Tomohisa Shoko, Takayuki Irahara, Ahmed O Hamedelneel, Noel Naidoo, A. R. K. Adesunkanmi, Yoshiro Kobe, AK Attri, Rajeev Sharma, Federico Coccolini, Tamer El Zalabany, Khalid Al Khalifa, Juan Sanjuán, Rita Barnabé, Wataru Ishii,

Tópico(s)

Amoebic Infections and Treatments

Resumo

Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high. The World Society of Emergency Surgery (WSES) has designed the CIAOW study in order to describe the clinical, microbiological, and management-related profiles of both community- and healthcare-acquired complicated intra-abdominal infections in a worldwide context. The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes patients undergoing surgery or interventional drainage to address complicated intra-abdominal infections. This preliminary report includes all data from almost the first two months of the six-month study period. Patients who met inclusion criteria with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study. 702 patients with a mean age of 49.2 years (range 18–98) were enrolled in the study. 272 patients (38.7%) were women and 430 (62.3%) were men. Among these patients, 615 (87.6%) were affected by community-acquired IAIs while the remaining 87 (12.4%) suffered from healthcare-associated infections. Generalized peritonitis was observed in 304 patients (43.3%), whereas localized peritonitis or abscesses was registered in 398 (57.7%) patients. The overall mortality rate was 10.1% (71/702). The final results of the CIAOW Study will be published following the conclusion of the study period in March 2013.

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