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Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides

2013; Multidisciplinary Digital Publishing Institute; Volume: 18; Issue: 10 Linguagem: Inglês

10.3390/molecules181011978

1433-1373

Nassir N. Al-Mohammed, Yatimah Alias, Zanariah Abdullah, Raied Mustafa Shakir, Ekhlass M. Taha, Aidil Abdul Hamid,

Phenothiazines and Benzothiazines Synthesis and Activities

Several new substituted sulfonamide compounds were synthesized and their structures were confirmed by ¹H-NMR, ¹³C-NMR, FT-IR, and mass spectroscopy. The antibacterial activities of the synthesized compounds were screened against standard strains of six Gram positive and four Gram negative bacteria using the microbroth dilution assay. Most of the compounds studied showed promising activities against both types of bacteria.