Portal de Periódicos da CAPES

Artigo Acesso aberto Produção Nacional Revisado por pares

BIBTEX RIS

ProtozoaDB: dynamic visualization and exploration of protozoan genomes

2007; Oxford University Press; Volume: 36; Issue: Database Linguagem: Inglês

10.1093/nar/gkm820

1362-4962

Alberto M. R. Dávila, Pablo N. Mendes, Glauber Wagner, Diogo A. Tschoeke, Rafael R. C. Cuadrat, Flávia Liberman, Lucas Vinícius Shigaki de Matos, Takahiko Satake, Kary Ocaña, Omar Triana‐Chávez, Sérgio Manuel Serra da Cruz, Henrique Jucá, Juliano C. Cury, Fábio Nascimento da Silva, Guilherme Arthur Gerônimo, Manuel Ruíz, Eduardo Ruback, Floriano Paes Silva, Christian Probst, Edmundo C. Grisard, Marco Aurélio Krieger, Samuel Goldenberg, Maria Cláudia Cavalcanti, Milton Ozório Moraes, María Luiza Machado Campos, Marta Mattoso,

Parasitic Infections and Diagnostics

ProtozoaDB (http://www.biowebdb.org/protozoadb) is being developed to initially host both genomics and post-genomics data from Plasmodium falciparum, Entamoeba histolytica, Trypanosoma brucei, T. cruzi and Leishmania major, but will hopefully host other protozoan species as more genomes are sequenced. It is based on the Genomics Unified Schema and offers a modern Web-based interface for user-friendly data visualization and exploration. This database is not intended to duplicate other similar efforts such as GeneDB, PlasmoDB, TcruziDB or even TDRtargets, but to be complementary by providing further analyses with emphasis on distant similarities (HMM-based) and phylogeny-based annotations including orthology analysis. ProtozoaDB will be progressively linked to the above-mentioned databases, focusing in performing a multi-source dynamic combination of information through advanced interoperable Web tools such as Web services. Also, to provide Web services will allow third-party software to retrieve and use data from ProtozoaDB in automated pipelines (workflows) or other interoperable Web technologies, promoting better information reuse and integration. We also expect ProtozoaDB to catalyze the development of local and regional bioinformatics capabilities (research and training), and therefore promote/enhance scientific advancement in developing countries.