Hamartomatous Polyp of Brunner's Glands
1963; Elsevier BV; Volume: 44; Issue: 1 Linguagem: Inglês
10.1016/s0016-5085(63)80119-5
ISSN1528-0012
Autores Tópico(s)Cholangiocarcinoma and Gallbladder Cancer Studies
ResumoPathologic proliferation of Brunner's glands, variously described as adenoma, adenomatous polyp, polyp, circumscribed nodular hyperplasia, and diffuse hyperplasia, is rare.A review of the English literature l -24 has disclosed only 25 such cases.Twenty additional cases 9 , 25, 26 have been mentioned briefly, without accompanying clinicopathologic data.Roentgenologic examination of the duodenum suggests the condition by the demonstration of single or multiple rounded filling defects that are often pedunculated and mobile, although other polypoid growths in this location may produce a similar appearance.This report is devoted to a description of a case of a pedunculated polyp of the second portion of the duodenum that proved to be a hamartoma of Brunner's glands.The pathogenesis and pathologic anatomy of this condition are reviewed. Case ReportA 50-year-old Chinese woman was admitted to San Francisco General Hospital on September 4, 1956, complaining of generalized weakness and the passage of tarry stools during the preceding 4 days.Two months before admission she had npted the onset of episodic, gnawing epigastric pain, without radiation, occurring in the late evening.The pain was relieved only slightly by food, milk, and antacids.Four days before admission exertional dyspnea, palpitations, and generalized weakness occurred, associated with the passage of several tarry stools.There was no
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