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HELIQUEST: a web server to screen sequences with specific α-helical properties

2008; Oxford University Press; Volume: 24; Issue: 18 Linguagem: Inglês

10.1093/bioinformatics/btn392

ISSN

1367-4811

Autores

Romain Gautier, Dominique Douguet, Bruno Antonny, Guillaume Drin,

Tópico(s)

Enzyme Structure and Function

Resumo

Abstract Summary: HELIQUEST calculates the physicochemical properties and amino acid composition of an α-helix and screens databank to identify protein segments possessing similar features. This server is also dedicated to mutating helices manually or automatically by genetic algorithm to design analogues of defined features. Availability: http://heliquest.ipmc.cnrs.fr Contact: gautier@ipmc.cnrs.fr

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