Produção Nacional
Revisado por pares
SYNTHESIS AND EVALUATION OF OCTOCRYLENE-INSPIRED COMPOUNDS FOR UV-FILTER ACTIVITY
2014; Brazilian Chemical Society; Linguagem: Inglês
10.5935/0100-4042.20140160
ISSN1678-7064
AutoresHudson Polonini, Rosângela da Silva Lopes, Adilson Beatriz, Roberto da Silva Gomes, Adriano O. Silva, Ricardo Vieira de Lima, Gláucia. A. Nunes, Marcos Antônio Fernandes Brandão, Nádia Rezende Barbosa Raposo, Dênis Pires de Lima,
Tópico(s)Photodynamic Therapy Research Studies
ResumoOctocrylene (2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate) is present in several sunscreens and is known to work synergistically with UV filters.We prepared eight octocrylene-related compounds to test their photoprotective activities by measuring diffuse transmittance.The compounds had varied photoprotection profiles, with Sun Protection Factors (SPF) ranging from 1 to 5 and UVA Protection Factors (UVAPF) ranging from 1 to 8. Compounds 4, 5, and 7 showed the best protection against UVB sunrays, while compounds 5, 6, and 7 presented the best results for protection from UVA, so compound 7 had the most balanced protection overall.Results for compounds 4, 8, and 9 are reported for the first time in the literature.
Referência(s)