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Combinational numeral fingerprint spectra of Glycyrrhiza and analysis of common peak ratio invariableness in HPLC

2006; Wiley; Volume: 20; Issue: 6-7 Linguagem: Inglês

10.1002/bmc.639

1099-0801

Huabin Zou, Guo‐Sheng Yang, Aiqin Du, Jiurong Yuan, Zhengran Qin, Yingying Xia, Hassan Y. Aboul‐Enein,

Natural product bioactivities and synthesis

To overcome the instability of traditional Chinese medicine (TCM) fingerprint spectra (FPS) and to build up absolute identification standard of TCM, the construction method of combinational numeral fingerprint spectra (CNFPS) was set up. The analysis of invariableness based on CNFPS was carried out. It can be used as absolute quantitative standard to identify the difference of TCM samples. According to this method, the HPLC FPS of components extracted from Glycyrrhiza root samples by ethanol was analyzed. Stable results and accurate quality evaluation were obtained perfectly. The common peak ratio invariableness is an absolute standard in identifying TCM samples, which is better than the similarity method of the FPS.