Portal de Periódicos da CAPES

Using Smell To Triage Samples in Point‐of‐Care Assays

2012; Wiley; Volume: 51; Issue: 44 Linguagem: Inglês

10.1002/anie.201207008

1521-3773

Hemakesh Mohapatra, Scott T. Phillips,

Mosquito-borne diseases and control

Smell of success: Reagent 1 provides the dual readouts of odor (ethanethiol) and fluorescence (derivative of 7-hydroxycoumarin) and can be used in down-selection assays based on smell and quantitative fluorescence assays of the samples that give a positive result. An important feature of 1 is the matched sensitivity of the two outputs. This reagent is designed for use in resource-limited settings and is demonstrated in assays that detect enzymes. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.