Produção Nacional
Revisado por pares
Pseudoresistant hypertension due to poor medication adherence
2014; Elsevier BV; Volume: 172; Issue: 2 Linguagem: Inglês
10.1016/j.ijcard.2013.12.181
ISSN1874-1754
AutoresAlfredo Dias de Oliveira‐Filho, Francisco A. Costa, Sabrina Joany Felizardo Neves, Divaldo Pereira de Lyra, Donald E. Morisky,
Tópico(s)Pharmaceutical Economics and Policy
ResumoResistant hypertension (RHTN) can be defined as the failure to achieve the goal blood pressure (less than 140/90 mm Hg, for the overall population, and less than 130/80 mm Hg for those with diabetes mellitus, or chronic kidney disease) when a patient adheres to a combination of at least 3 optimally dosed antihypertensive drugs of different classes, one of which should ideally be a diuretic [ [1] Calhoun D.A. Jones D. Textor S. et al. American Heart Association Professional Education Committee. Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Circulation. 2008 Jun 24; 117: e510-e526 Crossref PubMed Google Scholar ]. This definition does not apply to patients who have been recently diagnosed with hypertension [ [2] Moser M. Setaro J.F. Clinical practice. Resistant or difficult-to-control hypertension. N Engl J Med. 2006 Jul 27; 355: 385-392 Crossref PubMed Scopus (180) Google Scholar ]. Patients requiring four or more antihypertensive medications – even if controlled – are also classified as having resistant hypertension [ [3] Pimenta E. Calhoun D.A. Oparil S. Mechanisms and treatment of resistant hypertension. Arq Bras Cardiol. 2007 Jun; 88: 683-692 Crossref PubMed Google Scholar ].
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