Artigo Acesso aberto Revisado por pares

Worldwide Dissemination of the bla OXA-23 Carbapenemase Gene of Acinetobacter baumannii 1

2009; Centers for Disease Control and Prevention; Volume: 16; Issue: 1 Linguagem: Inglês

10.3201/eid1601.090852

ISSN

1080-6059

Autores

Pauline Mugnier, Laurent Poirel, Thierry Naas, Patrice Nordmann,

Tópico(s)

Bacterial biofilms and quorum sensing

Resumo

Abstract To assess dissemination of OXA-23–producing strains of Acinetobacter baumannii, we obtained 20 carbapenem-resistant, OXA-23–producing isolates from different regions. Their clonal relationship was assessed by pulsed-field gel electrophoresis and multilocus sequence typing. We identified 8 sequence types, including 4 novel types. All except 2 strains belonged to 2 main European clonal lineages. The blaOXA-23 gene was either located on the chromosome or on plasmids and associated with 4 genetic structures.

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