Portal de Periódicos da CAPES

Blood oxidative stress and lipoprotein oxidizability in haemodialysis patients: effect of the use of a vitamin E‐coated dialysis membrane

2000; Oxford University Press; Volume: 15; Issue: 12 Linguagem: Inglês

10.1093/ndt/15.12.2020

1460-2385

Dominique Bonnefont–Rousselot, Eric Lehmann, Marie‐Chantal Jaudon, Jacques Delattre, B Perrone, Jean‐Pierre Rechke,

Dialysis and Renal Disease Management

Background. Oxidative stress has been shown in haemodialysis patients in relation with an increased production of free radicals due to membrane‐induced complement and leukocyte activation. In order to minimize membrane bioincompatibility and thereby oxidative stress, more compatible filters have been perfected. Among them, a high‐flux vitamin E‐coated membrane (CL‐EE) has been proposed recently. In vivo, little data is available on the consequences of the use of vitamin E‐coated membranes. In the present study, the effects of a 3‐month use of CL‐EE dialysis membranes compared to conventional membranes have been evaluated in 12 haemodialysis patients on the blood oxidative stress status before and after the dialysis session.