InBr3–Et3N promoted alkynylation of aldehydes and N,O-acetals under mild conditions: facile and simple preparation of propargylic alcohols and amines
2003; Elsevier BV; Volume: 44; Issue: 22 Linguagem: Inglês
10.1016/s0040-4039(03)00931-6
ISSN1873-3581
AutoresNorio Sakai, Maki Hirasawa, Takeo Konakahara,
Tópico(s)Chemical Synthesis and Analysis
ResumoThe use of a novel InBr3–Et3N reagent system to promote addition reactions of 1-alkynes not only with a variety of aromatic or bulky aliphatic aldehydes but also with N,O-acetals is described. The corresponding propargylic alcohols or amines are produced in good to excellent yields.
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