Artigo Acesso aberto Revisado por pares

Assignment of the gene encoding DNA ligase I to human chromosome 19q13.2–13.3

1992; Elsevier BV; Volume: 12; Issue: 1 Linguagem: Inglês

10.1016/0888-7543(92)90422-o

ISSN

1089-8646

Autores

Deborah E. Barnes, Kenichi Kodama, Katherine Tynan, Barbara J. Trask, Mari Christensen, Pieter J. de Jong, Nigel K. Spurr, Tomas Lindahl, Harvey W. Mohrenweiser,

Tópico(s)

Genomics and Chromatin Dynamics

Resumo

The gene encoding DNA ligase I has been mapped on human chromosome 19 by analysis of rodent-human somatic cell hybrids informative for this chromosome and by two-color fluorescence in situ hybridization. The DNA ligase I gene (LIG1) is localized to 19q13.2–13.3 and is distal to ERCC1, the most telomeric of three DNA repair genes on this chromosome.

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