Generation and aldol reaction of enolate anion adjacent to a η3-alln-mo(co)2 Cp moiety. Anew approach to the to the stereoselective synthesis of 1,3,5-triol and 2-vinyl-3-hydroxyl-tetrahydrofuran.
1990; Elsevier BV; Volume: 31; Issue: 52 Linguagem: Inglês
10.1016/s0040-4039(00)97321-0
ISSN1873-3581
AutoresShie-Hsiung Lin, W.‐J. VONG, Cnih-Yi Cheng, Sue‐Lein Wang, Rai‐Shung Liu,
Tópico(s)Fluorine in Organic Chemistry
ResumoThe enolate of CpMo(CO)2(syn-η3-1-C3H4COCH3) generated with lithium diisopropylamide in THF undergoes diastereoselective aldol reaction with benzaldehyde; the alcohol thus formed has been utilized for stereoselective synthesis of 1.5-diphenyl-2-vinyl-pentan-1,3,5-triol and 2-vinyl-3-hydroxyl-5-phenyl-tetrahydrofuran.
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