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BIBTEX RIS

The role of radiotherapy in urinary bladder cancer: current status

2012; Sociedade Brasileira de Urologia; Volume: 38; Issue: 2 Linguagem: Inglês

10.1590/s1677-55382012000200002

1677-6119

Gustavo Nader Marta, Samir Abdallah Hanna, Rafael Gadia, Sebastião Francisco Miranda Corrêa, João Luís Fernandes da Silva, Heloísa de Andrade Carvalho,

Urological Disorders and Treatments

The role of radiotherapy (RT) in the treatment of urinary bladder cancer has undergone several modifications along the last decades. In the beginning, definitive RT was used as treatment in an attempt to preserve the urinary bladder; however, the results were poor compared to those of radical surgery. Recently, many protocols have been developed supporting the use of multi-modality therapy, and the concept of organ preservation began to be reconsidered. Although phase III randomized clinical studies comparing radical cystectomy with bladder preservation therapies do not exist, the conservative treatment may present low toxicity and high indexes of complete response for selected patients. The aim of this study was to review the literature on the subject in order to situate RT in the current treatment of urinary bladder cancer.