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Artigo Revisado por pares
BIBTEX RIS

Nickel‐Catalyzed Cross‐Coupling of Styrenyl Epoxides with Boronic Acids

2011; Wiley; Volume: 50; Issue: 27 Linguagem: Inglês

10.1002/anie.201101191

ISSN

1521-3773

Autores

Daniel K. Nielsen, Abigail G. Doyle,

Tópico(s)

Asymmetric Hydrogenation and Catalysis

Resumo

Let's get multicatalytic! A Ni0 catalyst complexed with a biaryldialkyl monophosphine ligand facilitates CC bond formation between styrenyl epoxides and aryl boronic acids (see scheme). X-ray analysis of a catalytically active nickel/ligand complex supports a redox pathway involving CO bond activation. A variety of α-substituted alcohols were generated with good reaction efficiency by a multicatalytic sequence.

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