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SELENIUM DEFICIENCY AND POSSIBLE INCREASED RISK OF CARCINOMA IN ADULTS WITH CYSTIC FIBROSIS

1985; Elsevier BV; Volume: 326; Issue: 8460 Linguagem: Inglês

10.1016/s0140-6736(85)90127-8

1474-547X

RobertJ. Stead, LesleyJ. Hinks, MargaretE. Hodson, A N Redington, BarbaraE. Clayton, J C Batten,

Air Quality and Health Impacts

20 young adults with cystic fibrosis (CF), including 2 with cancer, were found to have low serum selenium concentrations. Serum vitamin E concentrations were also low. It is suggested that low levels of circulating selenium are associated with increased risk of carcinoma, particularly in the presence of reduced vitamin E levels. Older patients with CF may be at increased risk for the development of carcinoma.