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First report of the blaOXA-58 gene in a clinical isolate of Acinetobacter baumannii in Rio de Janeiro, Brazil

2011; Instituto Oswaldo Cruz, Ministério da Saúde; Volume: 106; Issue: 3 Linguagem: Inglês

10.1590/s0074-02762011000300019

1678-8060

Deuseli Quaresma de Figueiredo, Kátia Regina Netto dos Santos, Eliezer Menezes Pereira, Ricardo Pinto Schuenck, Cláudia Rezende Vieira de Mendonça-Souza, Lúcia Martins Teixeira, Sílvia Susana Bona de Mondino,

Infections and bacterial resistance

Carbapenemase production is an important mechanism of carbapenem resistance among nonfermentative Gram-negative isolates. This study aimed to report the detection of blaOXA-58 gene in multiresistant clinical isolates of Acinetobacter baumannii recovered from inpatients in a public hospital. Polymerase chain reaction tests were performed to detect the blaOXA-23-like, blaOXA-24-like, blaOXA-58-like and blaOXA-51-like genes. The blaOXA-58 and blaOXA-23 genes were detected in one and three isolates, respectively. Sequencing of the blaOXA-58-like amplicon revealed 100% identity with the A. baumannii blaOXA-58 gene listed in the GenBank database. This is the first report of an OXA-58-producing A. baumannii isolate in Rio de Janeiro, Brazil.