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Spontaneous Splenic Rupture Associated with CMV Infection: Report of a Case and Review

2001; Informa; Volume: 33; Issue: 11 Linguagem: Inglês

10.1080/00365540110027114

1651-1980

Carol Alliot, Corinne Beets, Marie Besson, Philippe Derolland,

Liver Disease and Transplantation

The case of a 43-y-old healthy woman presenting with spontaneous splenic rupture is reported. The outcome was favourable after splenectomy. Although the diagnosis of CMV infection was established by serology, PCR and immunostaining, no viral inclusions were observed on spleen sections. The pathophysiology of the lesions was unclear given the multiple interactions of the virus with various cell populations, and particularly with the immune system.